SCHEMBL904460

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL904606	0.90	HPGD (0.46)	NOS2TSHRALDH1A1KDM4ESMN1; SMN2
	SCHEMBL904820	0.89	HPGD (0.47)	NOS2TSHRALDH1A1KDM4ESMN1; SMN2
	SCHEMBL904450	0.85	GAA (0.46)	RAB9ATSHRALDH1A1NPC1SMN1; SMN2
	SCHEMBL904628	0.83	TPSAB1 (0.47)	ALDH1A1
	SCHEMBL904457	0.83	ALDH1A1 (0.45)	NOS2ALDH1A1KDM4E
	SCHEMBL904546	0.82	NOS2 (0.53)	NOS2KDM4E
	SCHEMBL904816	0.82	ALDH1A1 (0.42)	NOS2TSHRALDH1A1KDM4ESMN1; SMN2
	SCHEMBL904433	0.82	CYP3A4 (0.43)	TSHRALDH1A1KDM4E
	SCHEMBL904809	0.82	ALDH1A1 (0.42)	NOS2TSHRALDH1A1KDM4ESMN1; SMN2
	SCHEMBL904415	0.81	ALDH1A1 (0.47)	NOS2ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.