Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044862 | 0.82 | PDE4D (0.51) | SMN1; SMN2KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL11269746 | 0.74 | HPGDS (0.61) | HPGDSADORA3SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL8751988 | 0.74 | ALDH1A1 (0.57) | SMN1; SMN2KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL1969117 | 0.72 | HPGDS (0.59) | HPGDSADORA3SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL9046330 | 0.72 | PDE4D (0.33) | — | |
| SCHEMBL3263722 | 0.71 | HPGDS (0.57) | HPGDSADORA3SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL10924593 | 0.70 | HPGDS (0.56) | HPGDSADORA3SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL3847496 | 0.70 | HPGDS (0.60) | HPGDSADORA3SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL17279852 | 0.70 | HPGDS (0.60) | HPGDSADORA3SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL10172532 | 0.68 | HPGDS (0.60) | HPGDSADORA3SMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749433-A1 | (4,4-DIFLUOROBUT-3-ENYLTHIO)-SUBSTITUTED HETEROCYCLIC OR CARBOCYCLIC RING COMPOUNDS HAVING PESTICIDAL ACTIVITY | ZENECA LIMITED (GB) | 1996-12-27 | — | — | EP | disclosed |