SCHEMBL9044877

SCHEMBL9044877

COc1cccc(/C=C/CC(=O)O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAM P19021 1/20 0.59
FOS P01100 1/20 0.58
JUN P05412 1/20 0.58
BCHE P06276 1/20 0.58
GRIK1 P39086 1/20 0.57
GRIK2 Q13002 1/20 0.57
CHRM2 P08172 1/20 0.57
CHRM1 P11229 1/20 0.57
CHRM3 P20309 1/20 0.57
MAOB P27338 4/20 0.55
RELA Q04206 1/20 0.54
ADORA3 P0DMS8 1/20 0.54
ADORA2A P29274 1/20 0.54
ADORA1 P30542 1/20 0.54
LMNA P02545 1/20 0.51
NFE2L2 Q16236 1/20 0.51
FBP1 P09467 1/20 0.51
MEN1 O00255 1/20 0.51
ALDH1A1 P00352 1/20 0.51
KMT2A Q03164 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7494930 1.00 PAM (0.59) PAMFOSJUNBCHEGRIK1
SCHEMBL5388781 0.85 FOS (0.56) FOSJUNBCHEGRIK1GRIK2
SCHEMBL5388778 0.85 FOS (0.56) FOSJUNBCHEGRIK1GRIK2
SCHEMBL17361873 0.83 CYP1A1 (0.55) PAMMEN1ALDH1A1KMT2ACYP1A1
SCHEMBL17361874 0.83 CYP1A1 (0.55) PAMMEN1ALDH1A1KMT2ACYP1A1
SCHEMBL12500127 0.82 LTB4R (0.54) FOSJUNBCHEGRIK1GRIK2
SCHEMBL3135246 0.81 LTB4R (0.58) FOSJUNBCHEGRIK1GRIK2
SCHEMBL3135249 0.81 LTB4R (0.58) FOSJUNBCHEGRIK1GRIK2
SCHEMBL30022662 0.81 NFE2L2 (0.68) FOSJUNBCHECHRM2CHRM1
SCHEMBL2998855 0.80 PAM (0.61) PAMBCHEGRIK1GRIK2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117510397-A Styrene acetate compound and preparation method and application thereof 青海大学 2024-02-06 CN disclosed
EP-0344577-B1 Butenoic or propenoic acid derivatives EISAI CO LTD (JP) 1996-10-09 EP disclosed
EP-0344577-A2 Butenoic or propenoic acid derivatives Eisai Co., Ltd. (JP) 1989-12-06 EP disclosed