Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.58 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.58 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.54 |
| ▸ | FOS | P01100 | 1/20 | 0.52 |
| ▸ | JUN | P05412 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3135249 | 1.00 | LTB4R (0.58) | LTB4RLTB4R2TBXAS1FOSJUN | |
| SCHEMBL12500127 | 0.96 | LTB4R (0.54) | LTB4RLTB4R2TBXAS1FOSJUN | |
| SCHEMBL5388778 | 0.90 | FOS (0.56) | FOSJUNBCHEGRIK1GRIK2 | |
| SCHEMBL5388781 | 0.90 | FOS (0.56) | FOSJUNBCHEGRIK1GRIK2 | |
| SCHEMBL8003031 | 0.83 | LTB4R (0.70) | LTB4RLTB4R2TBXAS1GRIK1GRIK2 | |
| SCHEMBL8080134 | 0.82 | LTB4R (0.69) | LTB4RLTB4R2TBXAS1GRIK1GRIK2 | |
| SCHEMBL1005789 | 0.82 | LTB4R (0.69) | LTB4RLTB4R2TBXAS1GRIK1GRIK2 | |
| SCHEMBL8080137 | 0.82 | LTB4R (0.69) | LTB4RLTB4R2TBXAS1GRIK1GRIK2 | |
| SCHEMBL1005790 | 0.82 | LTB4R (0.69) | LTB4RLTB4R2TBXAS1GRIK1GRIK2 | |
| SCHEMBL7494930 | 0.81 | PAM (0.59) | FOSJUNBCHEGRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268817-B2 | Substituted oxazole ketone modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-09-18 | — | — | US | disclosed |
| US-20100075931-A1 | Substituted oxazole ketone modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-03-25 | — | — | US | disclosed |
| EP-2068862-A2 | SUBSTITUTED OXAZOLE KETONE MODULATORS OF FATTY ACID AMIDE HYDROLASE | The Scripps Research Institute (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008030532-A2 | SUBSTITUTED OXAZOLE KETONE MODULATORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075931-A1 | Substituted oxazole ketone modulators of fatty acid amide hydrolase | FAAH, FAAH2, HCRTR2 | LTB4R 449/4885LTB4R2 315/4885TBXAS1 1627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.