Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TOP1 | P11387 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007518 | 0.90 | ALDH1A1 (0.49) | ALDH1A1TOP1KDM4EPOLBHSP90AA1 | |
| SCHEMBL9045225 | 0.86 | RORC (0.35) | ALDH1A1TOP1KDM4EPOLBHSP90AA1 | |
| SCHEMBL2087613 | 0.86 | LMNA (0.53) | ALDH1A1TOP1KDM4EPOLBHSP90AA1 | |
| SCHEMBL9443624 | 0.84 | LMNA (0.46) | ALDH1A1TOP1KDM4EPOLBRORC | |
| SCHEMBL9443566 | 0.83 | LMNA (0.54) | ALDH1A1TOP1KDM4EPOLBHSP90AA1 | |
| SCHEMBL9126186 | 0.81 | LMNA (0.53) | ALDH1A1TOP1KDM4ERORCLMNA | |
| SCHEMBL6216178 | 0.81 | LMNA (0.50) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL8094811 | 0.81 | LMNA (0.63) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL31683747 | 0.81 | LMNA (0.63) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL4659691 | 0.81 | KDM4E (0.46) | ALDH1A1TOP1KDM4EPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422485-B1 | Quinolone carboxylic acid derivatives, process for their preparation and their use | BAYER AG (DE) | 1996-04-03 | — | — | EP | disclosed |
| US-5300643-A | Viricides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| US-5217972-A | QUINOLONECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIVIRAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-06-08 | — | — | US | disclosed |
| EP-0422485-A2 | Quinolone carboxylic acid derivatives, process for their preparation and their use | BAYER AG (DE) | 1991-04-17 | — | — | EP | disclosed |