Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 3/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9443624 | 0.89 | LMNA (0.46) | KDM4EMAPTLMNAMEN1KMT2A | |
| SCHEMBL4659801 | 0.87 | ALDH1A1 (0.54) | KDM4EMAPTLMNAKMT2AHPGD | |
| SCHEMBL9126186 | 0.83 | LMNA (0.53) | KDM4ELMNAMEN1KMT2AHPGD | |
| SCHEMBL9045221 | 0.81 | ALDH1A1 (0.46) | KDM4ELMNAMEN1KMT2AHPGD | |
| SCHEMBL2087613 | 0.81 | LMNA (0.53) | KDM4ELMNAMEN1KMT2AHPGD | |
| SCHEMBL27346530 | 0.80 | ALDH1A1 (0.55) | KDM4EMAPTLMNAMEN1KMT2A | |
| SCHEMBL9443626 | 0.78 | LMNA (0.55) | KDM4ELMNAMEN1KMT2AHPGD | |
| SCHEMBL8094811 | 0.78 | LMNA (0.63) | KDM4ELMNAMEN1KMT2AHPGD | |
| SCHEMBL9443566 | 0.78 | LMNA (0.54) | KDM4ELMNAMEN1KMT2AHPGD | |
| SCHEMBL31683747 | 0.78 | LMNA (0.63) | KDM4ELMNAMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1503759-B1 | SUBSTITUTED QUINOLONE CARBOXYLIC ACIDS, THEIR DERIVATIVES, SITE OF ACTION, AND USES THEREOF | UNIV CALIFORNIA (US) | 2008-12-17 | — | — | EP | disclosed |
| US-20080176897-A1 | Substituted Quinolone Carboxylic Acids, Their Derivatives, Site of Action, And Uses Thereof | JOHNSTONE TIMOTHY B C | 2008-07-24 | — | — | US | disclosed |
| US-7355047-B2 | Substituted quinolone carboxylic acids, their derivatives, site of action, and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-04-08 | — | — | US | disclosed |
| US-20060178516-A1 | Substituted quinolone carboxylic acids, their derivatives, site of action, and uses thereof | OXFORD FINANCE CORPORATION | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178516-A1 | Substituted quinolone carboxylic acids, their derivatives, site of action, and uses thereof | GABRB2, GABRB1, GABRB3 | KDM4E 3010/4885MAPT 1863/4885LMNA 3881/4885 |
| US-20080176897-A1 | Substituted Quinolone Carboxylic Acids, Their Derivatives, Site of Action, And Uses Thereof | GABRB2, GABRB1, GABRB3 | KDM4E 3010/4885MAPT 1863/4885LMNA 3881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.