Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046936 | 0.83 | KMT2A (0.54) | LMNAKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL9046944 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDHSD17B10TOP1 | |
| SCHEMBL9044750 | 0.81 | ALDH1A1 (0.41) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL7011787 | 0.81 | ALDH1A1 (0.40) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL9045879 | 0.81 | ALDH1A1 (0.40) | ALDH1A1KDM4ETOP1HTTPOLB | |
| SCHEMBL9047564 | 0.81 | ALDH1A1 (0.40) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL9047265 | 0.81 | ALDH1A1 (0.40) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL9048751 | 0.81 | TOP1 (0.45) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL9048305 | 0.80 | LMNA (0.47) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL9045251 | 0.80 | LMNA (0.47) | LMNAKMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700912-A1 | QUINOLONE DERIVATIVE OR SALT THEREOF, AND ANTIBACTERIAL CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1996-03-13 | — | — | EP | disclosed |