Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 3/20 | 0.41 |
| ▸ | TOP2A | P11388 | 7/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046944 | 0.90 | ALDH1A1 (0.53) | TOP1ALDH1A1POLBKDM4EHSP90AA1 | |
| SCHEMBL9046444 | 0.85 | STAT3 (0.51) | ALDH1A1POLBKDM4EHTTHPGD | |
| SCHEMBL9045781 | 0.85 | CYP3A4 (0.50) | TOP1ALDH1A1POLBKDM4EHSP90AA1 | |
| SCHEMBL9047265 | 0.83 | ALDH1A1 (0.40) | TOP1ALDH1A1POLBKDM4EHSP90AA1 | |
| SCHEMBL9045282 | 0.81 | LMNA (0.43) | TOP1ALDH1A1POLBKDM4EHSP90AA1 | |
| SCHEMBL7011899 | 0.80 | TOP2A (0.38) | TOP1ALDH1A1POLBKDM4EHSP90AA1 | |
| SCHEMBL7005411 | 0.80 | CYP3A4 (0.52) | TOP1ALDH1A1POLBKDM4EHSP90AA1 | |
| SCHEMBL9048080 | 0.79 | ALDH1A1 (0.55) | TOP1ALDH1A1POLBKDM4EHSP90AA1 | |
| SCHEMBL7859676 | 0.77 | TOP1 (0.47) | TOP1ALDH1A1POLBKDM4EHSP90AA1 | |
| SCHEMBL7004678 | 0.77 | CYP3A4 (0.48) | TOP1ALDH1A1POLBKDM4EHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700912-A1 | QUINOLONE DERIVATIVE OR SALT THEREOF, AND ANTIBACTERIAL CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1996-03-13 | — | — | EP | disclosed |