Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CXCR5 | P32302 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045316 | 0.86 | HPGD (0.50) | HPGDKDM4EALDH1A1HSD17B10CXCR5 | |
| SCHEMBL28638059 | 0.84 | CXCR5 (0.47) | BRPF1HPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL9045271 | 0.83 | GABRA1 (0.37) | KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9046816 | 0.83 | KMT2A (0.41) | KDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL9047503 | 0.83 | AKR1B1 (0.41) | HPGDALDH1A1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL13148436 | 0.82 | CXCR5 (0.50) | BRPF1HPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL9047582 | 0.81 | LMNA (0.50) | HPGDKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9056727 | 0.81 | GABRA1 (0.43) | HPGDSMN1; SMN2LMNACYP3A4KMT2A | |
| SCHEMBL9047730 | 0.81 | CA2 (0.35) | KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL17059414 | 0.81 | TAAR1 (0.41) | BRPF1HPGDKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690854-A1 | 1-PHENYL-IMIDAZOL-2-ONE BIPHENYLMETHYL COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1996-01-10 | — | — | EP | disclosed |