Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.30 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.30 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047787 | 0.88 | ALOX15 (0.38) | CA2GABRA1GABRB2NR1H4ALDH1A1 | |
| SCHEMBL9047469 | 0.84 | CA2 (0.34) | CA2GABRA1GABRB2NR1H4NLRP3 | |
| SCHEMBL9046662 | 0.82 | CA2 (0.41) | CA2GABRA1GABRB2ALDH1A1TDP1 | |
| SCHEMBL9045526 | 0.81 | BRPF1 (0.39) | LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9046816 | 0.78 | KMT2A (0.41) | SMN1; SMN2ALDH1A1GAATDP1KDM4E | |
| SCHEMBL9047503 | 0.78 | AKR1B1 (0.41) | LMNASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL9045271 | 0.78 | GABRA1 (0.37) | GABRA1GABRB2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9044072 | 0.77 | GABRA1 (0.46) | CA2GABRA1GABRB2NLRP3SMN1; SMN2 | |
| SCHEMBL9044908 | 0.76 | GABRA1 (0.38) | CA2GABRA1GABRB2NLRP3 | |
| SCHEMBL9056727 | 0.76 | GABRA1 (0.43) | CA2GABRA1GABRB2NLRP3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690854-A1 | 1-PHENYL-IMIDAZOL-2-ONE BIPHENYLMETHYL COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1996-01-10 | — | — | EP | disclosed |