Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | GHSR | Q92847 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045869 | 0.81 | LMNA (0.51) | LMNARECQLALDH1A1MEN1KMT2A | |
| SCHEMBL28695962 | 0.81 | LMNA (0.86) | LMNARECQLALDH1A1MEN1KMT2A | |
| SCHEMBL9568092 | 0.80 | GHSR (0.49) | P2RX7GHSRMTNR1AMTNR1BFAAH | |
| SCHEMBL9568170 | 0.79 | P2RX7 (0.45) | LMNAP2RX7GHSRMTNR1AMTNR1B | |
| SCHEMBL366547 | 0.78 | P2RX7 (0.55) | P2RX7GHSRMTNR1AMTNR1BFAAH | |
| SCHEMBL9045885 | 0.78 | PTGIR (0.58) | LMNA | |
| SCHEMBL9045875 | 0.78 | LMNA (0.47) | LMNAMTNR1AMTNR1BALDH1A1KMT2A | |
| SCHEMBL6642213 | 0.77 | GHSR (0.69) | LMNAP2RX7GHSRALDH1A1MEN1 | |
| SCHEMBL6584070 | 0.76 | P2RX7 (0.53) | P2RX7GHSRMTNR1AMTNR1BFAAH | |
| SCHEMBL8569917 | 0.76 | GHSR (0.57) | P2RX7GHSRMTNR1AMTNR1BFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |