Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047483 | 0.86 | ACHE (0.40) | ACHESIGMAR1MEN1KMT2ADRD4 | |
| SCHEMBL8858393 | 0.83 | PTGIR (0.52) | NR1H3 | |
| SCHEMBL8858498 | 0.80 | GHSR (0.45) | ACHEMEN1KMT2ACA1CA2 | |
| SCHEMBL8858509 | 0.79 | CA1 (0.39) | ACHESIGMAR1MEN1KMT2ADRD4 | |
| SCHEMBL9048669 | 0.77 | MEN1 (0.42) | MEN1KMT2AOXTRAVPR1A | |
| SCHEMBL9568094 | 0.75 | MEN1 (0.49) | MEN1KMT2A | |
| SCHEMBL9050857 | 0.74 | PTGIR (0.43) | ACHESIGMAR1 | |
| SCHEMBL8858504 | 0.74 | MEN1 (0.39) | MEN1KMT2ANR1H3OXTRAVPR1A | |
| SCHEMBL9047490 | 0.74 | ACHE (0.40) | ACHESIGMAR1KMT2ADRD4CA1 | |
| SCHEMBL9427328 | 0.72 | SIGMAR1 (0.44) | ACHESIGMAR1OXTRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |