Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048489 | 0.86 | ACHE (0.36) | ACHETAS1R3TAS1R1TAS1R2CA1 | |
| SCHEMBL9047496 | 0.84 | TAS1R3 (0.40) | ACHETAS1R3TAS1R1TAS1R2CA1 | |
| SCHEMBL9050857 | 0.82 | PTGIR (0.43) | ACHESIGMAR1 | |
| SCHEMBL28069851 | 0.81 | CA1 (0.56) | TAS1R3TAS1R1TAS1R2CA1CA2 | |
| SCHEMBL8858478 | 0.79 | PTGIR (0.54) | KMT2A | |
| SCHEMBL9050863 | 0.79 | PTGIR (0.50) | DRD4SIGMAR1 | |
| SCHEMBL9050353 | 0.76 | ACHE (0.43) | ACHEBCHEMAOAMAOB | |
| SCHEMBL27734664 | 0.75 | ADRA2A (0.47) | TAS1R3TAS1R1TAS1R2SIGMAR1 | |
| SCHEMBL29062395 | 0.74 | RXRA (0.48) | KMT2A | |
| SCHEMBL6242626 | 0.74 | MAOA (0.50) | ACHECA1CA2KMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |