Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PDE9A | O76083 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046169 | 0.81 | CRHR1 (0.39) | CRHR1KDM4E | |
| SCHEMBL9045192 | 0.76 | DYRK1A (0.34) | CRHR1KDM4EALDH1A1LMNA | |
| SCHEMBL9045141 | 0.73 | CRHR1 (0.39) | CRHR1KDM4EALDH1A1LMNA | |
| SCHEMBL9046257 | 0.72 | KDM4E (0.42) | CRHR1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9045363 | 0.70 | CRHR1 (0.37) | CRHR1TLR9TLR8TLR7KDM4E | |
| SCHEMBL1506620 | 0.60 | S1PR1 (0.46) | CRHR1ALDH1A1LMNA | |
| SCHEMBL13097696 | 0.60 | CRHR1 (0.40) | CRHR1KDM4EALDH1A1LMNA | |
| SCHEMBL9046491 | 0.58 | CRHR1 (0.41) | CRHR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6416771 | 0.58 | ALDH1A1 (0.38) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9046510 | 0.58 | MCL1 (0.40) | CRHR1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723533-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-07-31 | — | — | EP | disclosed |