Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568045 | 0.85 | TAOK1 (0.39) | TBXAS1TRPM8NR1I2TAOK1ALDH1A1 | |
| SCHEMBL9048009 | 0.83 | TBXAS1 (0.44) | TBXAS1TRPM8NR1I2 | |
| SCHEMBL9048217 | 0.82 | TRPM8 (0.34) | TBXAS1TRPM8NR1I2TAOK1ABCB1 | |
| SCHEMBL9047215 | 0.82 | TBXAS1 (0.57) | TBXAS1 | |
| SCHEMBL9427232 | 0.76 | PTGIR (0.36) | TRPM8ALDH1A1 | |
| SCHEMBL9427435 | 0.76 | PTGIR (0.33) | TRPM8 | |
| SCHEMBL9048118 | 0.75 | PTGIR (0.36) | TRPM8 | |
| SCHEMBL9046447 | 0.72 | KDM4C (0.39) | TBXAS1TRPM8NR1I2TAOK1 | |
| SCHEMBL9427288 | 0.67 | TBXAS1 (0.40) | TBXAS1TRPM8NR1I2 | |
| SCHEMBL9049514 | 0.66 | PTGIR (0.36) | TBXAS1ALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |