Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048005 | 0.85 | TBXAS1 (0.37) | TAOK1TRPM8ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9048009 | 0.83 | TBXAS1 (0.44) | TRPM8SLC6A2SLC6A4SLC6A3NR1I2 | |
| SCHEMBL9047215 | 0.82 | TBXAS1 (0.57) | TBXAS1 | |
| SCHEMBL3825017 | 0.71 | GBA1 (0.41) | ALDH1A1SMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL9568024 | 0.70 | KDM4C (0.48) | TAOK1TRPM8ALDH1A1TBXAS1 | |
| SCHEMBL9568005 | 0.69 | TRPM8 (0.39) | TRPM8 | |
| SCHEMBL2597095 | 0.68 | MTNR1A (0.46) | — | |
| SCHEMBL9051601 | 0.67 | TRPM8 (0.32) | TAOK1TRPM8NR1I2SLC18A3 | |
| SCHEMBL9568049 | 0.67 | TBXAS1 (0.44) | TAOK1ADRB3ALDH1A1MAPTSLC6A4 | |
| SCHEMBL3611898 | 0.66 | PLAU (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |