Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 4/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568061 | 0.78 | PTGIR (0.36) | PTGIRSLC18A3 | |
| SCHEMBL9427490 | 0.76 | MEN1 (0.39) | PTGIRKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9050149 | 0.72 | GHSR (0.33) | PTGIRCYP3A4 | |
| SCHEMBL9426462 | 0.67 | CA1 (0.35) | PTGIRKDM4E | |
| SCHEMBL9047804 | 0.67 | PTGIR (0.42) | PTGIRTBXAS1 | |
| SCHEMBL9048005 | 0.66 | TBXAS1 (0.37) | KDM4EALDH1A1TBXAS1HTT | |
| SCHEMBL9047616 | 0.65 | PTGIR (0.43) | PTGIR | |
| SCHEMBL9045869 | 0.65 | LMNA (0.51) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9049789 | 0.65 | PTGIR (0.41) | PTGIRCYP3A4 | |
| SCHEMBL9049907 | 0.65 | MTNR1A (0.33) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |