Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | PTGIR | P43119 | 17/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427288 | 0.86 | TBXAS1 (0.40) | TBXAS1PTGIRPTGDRCA1CA2 | |
| SCHEMBL9049911 | 0.80 | PTGIR (0.39) | PTGIRCA1CA2ACHE | |
| SCHEMBL9427494 | 0.79 | DRD2 (0.40) | PTGIRCA1CA2ACHE | |
| SCHEMBL9050151 | 0.78 | PTGIR (0.39) | TBXAS1PTGIRCA1CA2ACHE | |
| SCHEMBL9048009 | 0.77 | TBXAS1 (0.44) | TBXAS1PTGIRPTGDR | |
| SCHEMBL9427442 | 0.77 | PTGIR (0.41) | PTGIRCA1CA2ACHE | |
| SCHEMBL9047809 | 0.75 | TBXAS1 (0.43) | TBXAS1PTGIR | |
| SCHEMBL9049164 | 0.75 | MTNR1A (0.41) | PTGIRCA1CA2ACHE | |
| SCHEMBL9568065 | 0.74 | KCNA5 (0.30) | — | |
| SCHEMBL9047207 | 0.74 | TBXAS1 (0.52) | TBXAS1PTGIRPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |