Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 11/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311345 | 0.81 | OPRL1 (0.43) | OPRL1OPRM1GRIA2 | |
| SCHEMBL8316610 | 0.80 | OPRL1 (0.42) | OPRL1OPRM1GRIA2CA12CA9 | |
| SCHEMBL904818 | 0.77 | OPRL1 (0.48) | OPRL1OPRM1GRIA2CA12CA9 | |
| SCHEMBL14094159 | 0.74 | OPRL1 (0.39) | OPRL1OPRM1ALDH1A1 | |
| SCHEMBL24567751 | 0.74 | PER2 (0.50) | ALDH1A1HPGDKDM4EPSEN1PSEN2 | |
| SCHEMBL20857619 | 0.71 | PER2 (0.52) | ALDH1A1HPGDKDM4ECA12CA9 | |
| SCHEMBL17858470 | 0.70 | KDM4E (0.44) | OPRL1OPRM1ALDH1A1HPGDKDM4E | |
| SCHEMBL3285134 | 0.69 | SLC6A2 (0.45) | OPRL1OPRM1 | |
| SCHEMBL6866920 | 0.66 | OPRL1 (0.67) | OPRL1OPRM1GRIA2 | |
| SCHEMBL21400342 | 0.66 | ALDH1A1 (0.36) | ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |
| CN-1589153-A | Prevention or treatment of urinary disorders | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-03-02 | — | — | CN | disclosed |