Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 11/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904845 | 0.77 | OPRL1 (0.46) | OPRL1OPRM1CA12CA1CA2 | |
| SCHEMBL3285134 | 0.73 | SLC6A2 (0.45) | OPRL1OPRM1 | |
| SCHEMBL8311345 | 0.71 | OPRL1 (0.43) | OPRL1OPRM1GRIA2DRD4 | |
| SCHEMBL3319807 | 0.71 | DRD4 (0.42) | CA12CA1CA2CA4CA7 | |
| SCHEMBL8316610 | 0.70 | OPRL1 (0.42) | OPRL1OPRM1CA12CA2CA9 | |
| SCHEMBL6866920 | 0.69 | OPRL1 (0.67) | OPRL1OPRM1GRIA2 | |
| Hydrochloric Acid SCHEMBL11099579 | 0.68 | OPRL1 (0.66) | OPRL1OPRM1GRIA2 | |
| SCHEMBL4861065 | 0.68 | USP30 (0.48) | USP30MAOAMAOBDRD2DRD1 | |
| SCHEMBL18756604 | 0.68 | PER2 (0.46) | OPRM1MAOAMAOBDRD2DRD1 | |
| SCHEMBL4480156 | 0.67 | CA2 (0.43) | OPRL1OPRM1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |