Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | IAPP | P10997 | 4/20 | 0.46 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131222 | 0.89 | ERN1 (0.60) | ERN1POLBGAARAB9AIAPP | |
| SCHEMBL29356117 | 0.89 | ERN1 (0.60) | ERN1POLBGAARAB9AIAPP | |
| Acetone SCHEMBL22719929 | 0.84 | ERN1 (0.61) | ERN1POLBGAARAB9AIAPP | |
| Sulfuric Acid SCHEMBL8445673 | 0.83 | TRIM24 (0.52) | ERN1ALDH1A1HSD17B10CA1CA2 | |
| Ethylene Glycol SCHEMBL17292672 | 0.82 | ERN1 (0.52) | ERN1POLBGAARAB9AIAPP | |
| Acetic Acid SCHEMBL724536 | 0.81 | ERN1 (0.57) | ERN1POLBGAARAB9AIAPP | |
| Pyrogallol SCHEMBL27910417 | 0.79 | ALDH1A1 (0.57) | ERN1POLBGAARAB9AIAPP | |
| SCHEMBL7774684 | 0.78 | ERN1 (0.39) | ERN1POLBGAARAB9AIAPP | |
| SCHEMBL8336774 | 0.78 | TTR (0.39) | ERN1ALDH1A1TDP1CDK2 | |
| Sulfuric Acid SCHEMBL968452 | 0.78 | ALDH1A1 (0.48) | POLBGAAALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8012644-A | — | — | None | — | — | JP | disclosed |
| JP-H0812644-A | STYRENE SULFATE ESTER DERIVATIVE | RES DEV CORP OF JAPAN | 1996-01-16 | — | — | JP | disclosed |