Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13556486 | 0.86 | KMT2A (0.47) | KMT2AALDH1A1NPSR1HTTPOLB | |
| SCHEMBL16026437 | 0.83 | ALDH1A1 (0.83) | KMT2AALDH1A1NPSR1HTTMAPK1 | |
| SCHEMBL4544770 | 0.81 | ALDH1A1 (0.65) | ALDH1A1NPSR1HTTMAPK1TSHR | |
| SCHEMBL12788641 | 0.81 | ALDH1A1 (0.65) | KMT2AALDH1A1NPSR1HTTMAPK1 | |
| SCHEMBL17078787 | 0.80 | CHRNB2 (0.44) | KMT2AALDH1A1NPSR1HTTTHRB | |
| SCHEMBL17078785 | 0.80 | CHRNB2 (0.44) | KMT2AALDH1A1NPSR1HTTTHRB | |
| SCHEMBL29313174 | 0.79 | NPC1 (0.46) | KMT2AALDH1A1THRBTP53 | |
| SCHEMBL12788401 | 0.79 | ALDH1A1 (0.68) | KMT2AALDH1A1NPSR1HTTMAPK1 | |
| SCHEMBL13804475 | 0.79 | ALDH1A1 (0.71) | ALDH1A1NPSR1HTTMAPK1TSHR | |
| SCHEMBL1372147 | 0.79 | CYP1A2 (0.75) | ALDH1A1NPSR1HTTMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092067-A1 | APT1 and APT2 Inhibitors and Uses Thereof | CORNELL UNIVERSITY | 2025-03-20 | — | — | US | disclosed |
| CN-117820287-A | Magnolol derivative, and preparation method and application thereof | 中国药科大学 | 2024-04-05 | — | — | CN | disclosed |
| WO-2022246115-A1 | APT1 AND APT2 INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2022-11-24 | — | — | WO | disclosed |
| EP-0703908-A1 | ANALGESIC DIBENZOXAZEPINES AND DIBENZOTHIAZEPINES | G.D. SEARLE & CO. (US) | 1996-04-03 | — | — | EP | disclosed |
| US-5461047-A | Analgesics and treats prostaglandin-E2 mediated diseases in animals | G. D. SEARLE & CO. (US) | 1995-10-24 | — | — | US | disclosed |
| WO-1994029286-A1 | ANALGESIC DIBENZOXAZEPINES AND DIBENZOTHIAZEPINES | G.D. SEARLE & CO. (US) | 1994-12-22 | — | — | WO | disclosed |
| US-5354747-A | Analgesics | G. D. SEARLE & CO. (US) | 1994-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250092067-A1 | APT1 and APT2 Inhibitors and Uses Thereof | LYPLA2, LYPLA1, PPT1 | KMT2A 686/4885ALDH1A1 3083/4885NPSR1 4681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.