Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567950 | 0.89 | TRPM8 (0.48) | TRPM8MTNR1BECE1HTTALDH1A1 | |
| SCHEMBL5198565 | 0.83 | TRPM8 (0.44) | TRPM8ECE1HTTALDH1A1 | |
| SCHEMBL2406499 | 0.83 | HTT (0.45) | TRPM8ECE1HTTALDH1A1 | |
| SCHEMBL9048929 | 0.80 | TDP1 (0.36) | TRPM8ALDH1A1TDP1 | |
| SCHEMBL9568075 | 0.79 | TRPM8 (0.48) | TRPM8MTNR1BHTTALDH1A1 | |
| SCHEMBL9048942 | 0.78 | PTGIR (0.55) | — | |
| SCHEMBL9048934 | 0.78 | PTGIR (0.39) | TDP1 | |
| SCHEMBL8802816 | 0.76 | TSHR (0.50) | ECE1HTTHAO1ALDH1A1 | |
| SCHEMBL9568004 | 0.76 | TRPM8 (0.48) | TRPM8HTTHAO1ALDH1A1 | |
| SCHEMBL27385115 | 0.75 | TRPM8 (0.43) | TRPM8ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |