Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1507630 | 0.79 | CYP2D6 (0.42) | MAPTKMT2ACYP2D6CYP1A2KCNN4 | |
| SCHEMBL29021068 | 0.79 | GABRA1 (0.38) | LMNACHRM2CHRM1CHRM3HDAC3 | |
| SCHEMBL9049034 | 0.78 | MAPT (0.44) | MAPTKMT2ACYP2D6CYP1A2KCNN4 | |
| SCHEMBL4587493 | 0.78 | L3MBTL1 (0.43) | MAPTLMNAALDH1A1KDM4ETSHR | |
| SCHEMBL16314168 | 0.76 | MAPT (0.53) | MAPTKMT2ACYP2D6CYP1A2KCNN4 | |
| SCHEMBL9049025 | 0.75 | TRPA1 (0.51) | KMT2ACYP1A2CYP2C19HIF1ALMNA | |
| SCHEMBL11480693 | 0.74 | MAPK1 (0.46) | MAPTKMT2ACYP2D6CYP1A2KCNN4 | |
| SCHEMBL4589967 | 0.73 | HTT (0.44) | MAPTKMT2ACYP2D6CYP1A2CYP2C19 | |
| SCHEMBL9333684 | 0.73 | IRAK4 (0.36) | MAPTKMT2AALDH1A1KDM4ETSHR | |
| SCHEMBL109172 | 0.71 | MAPK1 (0.43) | MAPTKMT2ACYP2D6CYP1A2KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439616-A | THERMAL CRACKING, ACID CATALYST | AMERICAN CYANAMID COMPANY (US) | 1984-03-27 | — | — | US | claimed |
| US-7772351-B2 | grafted onto an ethylenically unsaturated monomer; paper, textile, detergents, paints; | COATEX S.A.S. (FR) | 2010-08-10 | — | — | US | disclosed |
| US-20060106186-A1 | grafted onto an ethylenically unsaturated monomer; paper, textile, detergents, paints; | COATEX S.A.S. (FR) | 2006-05-18 | — | — | US | disclosed |
| EP-0234353-B1 | PROCESS FOR THE PRODUCTION OF TETRAMETHYL XYLYLENE DIISOCYANATES | AMERICAN CYANAMID COMPANY (US) | 1992-04-22 | — | — | EP | disclosed |
| EP-0164491-B1 | PROCESS FOR THE PREPARATION OF TERTIARY ARALKYL URETHANES AND PROCESS FOR THE PREPARATION OF ISOCYANATES DERIVED THEREFROM | AMERICAN CYANAMID COMPANY (US) | 1990-05-09 | — | — | EP | disclosed |
| EP-0234353-A1 | Process for the production of tetramethyl xylylene diisocyanates | AMERICAN CYANAMID COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |
| EP-0164494-B1 | SYSTEM FOR CONVEYING CONICAL ARTICLES | YAMAKYU AUTOMATICS CO., LTD. (JP) | 1987-08-26 | — | — | EP | disclosed |
| EP-0164491-A1 | Process for the preparation of tertiary aralkyl urethanes and process for the preparation of isocyanates derived therefrom | AMERICAN CYANAMID COMPANY (US) | 1985-12-18 | — | — | EP | disclosed |
| EP-0101832-A1 | Tertiary aralkyl urethanes and isocyanates derived therefrom | AMERICAN CYANAMID COMPANY (US) | 1984-03-07 | — | — | EP | disclosed |