Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4589967 | 0.82 | HTT (0.44) | MAPTKMT2AKCNH2CYP2C19HIF1A | |
| SCHEMBL2969422 | 0.78 | MAPT (0.48) | MAPTKMT2AKCNH2CYP2C19HIF1A | |
| SCHEMBL1829558 | 0.75 | MAPT (0.48) | MAPTKMT2AKCNH2CYP2C19HIF1A | |
| SCHEMBL20416250 | 0.73 | LMNA (0.41) | MAPTCHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL28652308 | 0.72 | SRR (0.45) | CYP1A2PKMLMNA | |
| SCHEMBL22115533 | 0.71 | MAPT (0.33) | MAPTKMT2AKCNH2CYP2C19KIF11 | |
| SCHEMBL28356018 | 0.71 | SRR (0.44) | CYP1A2PKMLMNA | |
| SCHEMBL28356022 | 0.71 | SRR (0.44) | CYP1A2PKMLMNA | |
| SCHEMBL9305616 | 0.71 | SRR (0.47) | HIF1ACYP1A2SMN1; SMN2PKMLMNA | |
| SCHEMBL4377967 | 0.70 | CYP2C19 (0.46) | MAPTKMT2AKCNH2CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385456-B1 | High surface hardness transparent resin and polymerizable monomer | MITSUI TOATSU CHEMICALS (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5084538-A | HIGH SURFACE HARDNESS TRANSPARENT RESIN PREPARED FROM A COMPOUND HAVING AT LEAST ONE ISOPROPENYL PHENYL GROUP | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-01-28 | — | — | US | disclosed |