Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9099497 | 0.74 | NOS1 (0.44) | EPHX2ALDH1A1RECQL | |
| SCHEMBL8940793 | 0.73 | NOS1 (0.34) | ALDH1A1KDM4E | |
| SCHEMBL9097546 | 0.69 | NCF1 (0.39) | KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL9046922 | 0.68 | NOS1 (0.36) | ALDH1A1 | |
| SCHEMBL9099459 | 0.68 | BACE1 (0.44) | KMT2AALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL9426491 | 0.67 | ADORA3 (0.44) | EPHX2ALDH1A1 | |
| SCHEMBL9097235 | 0.67 | KDM4E (0.37) | KMT2AALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL9098537 | 0.67 | ALDH1A1 (0.35) | ALDH1A1KDM4ELMNA | |
| SCHEMBL9047243 | 0.66 | NOS1 (0.34) | KMT2AEPHX2ALDH1A1RECQLKDM4E | |
| SCHEMBL9098247 | 0.66 | ADORA3 (0.36) | KMT2AEPHX2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412404-B1 | Thiazole derivatives, processes for production thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-01-31 | — | — | EP | disclosed |
| US-5369107-A | Thiazole derivatives, processes for production thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-29 | — | — | US | disclosed |
| US-5256675-A | Antirheumatic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| EP-0412404-A2 | Thiazole derivatives, processes for production thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-13 | — | — | EP | disclosed |