Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | ILK | Q13418 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9099556 | 0.85 | BACE1 (0.44) | BACE1GFERAPPPIK3CAPIK3CD | |
| SCHEMBL9097546 | 0.81 | NCF1 (0.39) | BACE1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL9426724 | 0.74 | ALDH1A1 (0.34) | GFERAXLALDH1A1LMNA | |
| SCHEMBL9098537 | 0.71 | ALDH1A1 (0.35) | PDGFRBPDGFRAKDM4EALDH1A1LMNA | |
| SCHEMBL9097235 | 0.71 | KDM4E (0.37) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL9099497 | 0.70 | NOS1 (0.44) | BACE1ALDH1A1MAPTTDP1 | |
| SCHEMBL9099767 | 0.68 | BACE1 (0.46) | BACE1GFERAXLAPPPDGFRB | |
| SCHEMBL9049092 | 0.68 | KMT2A (0.36) | KDM4EMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL9097968 | 0.67 | ADORA3 (0.46) | BACE1GFERAXLAPPPDGFRB | |
| SCHEMBL8940793 | 0.66 | NOS1 (0.34) | PIK3CAPIK3CDPI4KAPIK3CGPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030370-A2 | THIAZOLE AND THIADIAZOLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS USEFUL IN THE TREATMENT OF THROMBOCYTOPENIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-03 | — | — | WO | disclosed |