Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045862 | 0.82 | KDM4E (0.47) | LMNACRHR1 | |
| SCHEMBL9046491 | 0.80 | CRHR1 (0.41) | LMNACRHR1 | |
| SCHEMBL9046572 | 0.77 | CRHR1 (0.43) | ADORA2AADORA1CRHR1 | |
| SCHEMBL9057759 | 0.74 | LMNA (0.39) | LMNAHDAC6CRHR1 | |
| SCHEMBL9045363 | 0.72 | CRHR1 (0.37) | LMNAADORA2AADORA1CRHR1 | |
| SCHEMBL9047218 | 0.71 | CRHR1 (0.43) | LMNAADORA2AADORA1CRHR1 | |
| SCHEMBL20470633 | 0.69 | ADORA2A (0.49) | ADORA2AADORA1 | |
| SCHEMBL890252 | 0.68 | TSHR (0.39) | ADORA2AADORA1 | |
| SCHEMBL9045141 | 0.66 | CRHR1 (0.39) | LMNACRHR1 | |
| SCHEMBL31661019 | 0.65 | ADORA2A (0.65) | LMNAADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723533-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-07-31 | — | — | EP | disclosed |