Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057759 | 0.88 | LMNA (0.39) | KDM4EMEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL9046491 | 0.88 | CRHR1 (0.41) | KDM4EMEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL9046572 | 0.84 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL9047218 | 0.83 | CRHR1 (0.43) | KDM4EMEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL9049223 | 0.82 | EIF4A3 (0.36) | LMNACRHR1 | |
| SCHEMBL9045141 | 0.72 | CRHR1 (0.39) | KDM4EALDH1A1LMNACRHR1 | |
| SCHEMBL9045363 | 0.70 | CRHR1 (0.37) | KDM4EKMT2ALMNACRHR1 | |
| SCHEMBL1762674 | 0.66 | LMNA (0.58) | ALDH1A1LMNACRHR1 | |
| SCHEMBL9046169 | 0.65 | CRHR1 (0.39) | KDM4ECRHR1 | |
| SCHEMBL7678043 | 0.65 | MAPT (0.59) | MEN1ALDH1A1KMT2ALMNACRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723533-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-07-31 | — | — | EP | claimed |
| EP-0723533-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-07-31 | — | — | EP | disclosed |