Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 15/20 | 0.57 |
| ▸ | DRD2 | P14416 | 14/20 | 0.57 |
| ▸ | DRD4 | P21917 | 14/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 4/20 | 0.48 |
| ▸ | HRH1 | P35367 | 4/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904897 | 0.91 | DRD2 (0.58) | DRD3DRD2DRD4CYP3A4CYP2D6 | |
| SCHEMBL905002 | 0.91 | DRD3 (0.57) | DRD3DRD2DRD4CYP3A4CYP2D6 | |
| SCHEMBL905011 | 0.90 | DRD2 (0.71) | DRD3DRD2DRD4 | |
| SCHEMBL904878 | 0.88 | DRD2 (0.55) | DRD3DRD2DRD4CYP3A4CYP2D6 | |
| SCHEMBL904917 | 0.85 | DRD3 (0.52) | DRD3DRD2DRD4CYP3A4CYP2D6 | |
| SCHEMBL904879 | 0.84 | CYP3A4 (0.53) | DRD3DRD2DRD4CYP3A4CYP2D6 | |
| SCHEMBL904854 | 0.83 | DRD3 (0.50) | DRD3DRD2DRD4CYP3A4CYP2D6 | |
| SCHEMBL904887 | 0.82 | OPRM1 (0.71) | DRD3DRD2DRD4HTR1AHTR2A | |
| SCHEMBL904925 | 0.81 | OPRM1 (0.52) | DRD3DRD2DRD4CYP3A4CYP2D6 | |
| SCHEMBL904920 | 0.81 | DRD2 (0.65) | DRD3DRD2DRD4CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |