Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | MTOR | P42345 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | THPO | P40225 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | EBP | Q15125 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 8/20 | 0.49 |
| ▸ | DRD2 | P14416 | 7/20 | 0.49 |
| ▸ | HTR2A | P28223 | 7/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904917 | 0.90 | DRD3 (0.52) | OPRM1OPRD1OPRL1CYP3A4CYP2D6 | |
| SCHEMBL904878 | 0.89 | DRD2 (0.55) | OPRM1OPRD1CYP3A4CYP2D6MAPK1 | |
| SCHEMBL904854 | 0.88 | DRD3 (0.50) | OPRM1OPRD1OPRL1CYP3A4CYP2D6 | |
| SCHEMBL905002 | 0.88 | DRD3 (0.57) | OPRM1OPRD1OPRL1CYP3A4CYP2D6 | |
| SCHEMBL11755595 | 0.85 | ABCB11 (0.73) | CYP3A4CYP2D6MAPK1MTORTSHR | |
| SCHEMBL904874 | 0.85 | TACR3 (0.57) | OPRM1OPRD1OPRL1CYP3A4CYP2D6 | |
| SCHEMBL904887 | 0.84 | OPRM1 (0.71) | OPRM1OPRD1OPRL1DRD3DRD2 | |
| SCHEMBL904893 | 0.83 | OPRM1 (0.75) | OPRM1OPRD1OPRL1CYP3A4CYP2D6 | |
| SCHEMBL904897 | 0.82 | DRD2 (0.58) | OPRM1OPRD1CYP3A4CYP2D6MAPK1 | |
| SCHEMBL904932 | 0.81 | DRD3 (0.57) | OPRM1OPRD1CYP3A4CYP2D6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |