Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 19/20 | 0.71 |
| ▸ | DRD4 | P21917 | 17/20 | 0.71 |
| ▸ | DRD3 | P35462 | 17/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904897 | 0.91 | DRD2 (0.58) | DRD2DRD4DRD3LMNA | |
| SCHEMBL905002 | 0.91 | DRD3 (0.57) | DRD2DRD4DRD3LMNA | |
| SCHEMBL904932 | 0.90 | DRD3 (0.57) | DRD2DRD4DRD3 | |
| SCHEMBL904878 | 0.88 | DRD2 (0.55) | DRD2DRD4DRD3 | |
| SCHEMBL904887 | 0.85 | OPRM1 (0.71) | DRD2DRD4DRD3 | |
| SCHEMBL904917 | 0.85 | DRD3 (0.52) | DRD2DRD4DRD3LMNASIGMAR1 | |
| SCHEMBL904871 | 0.84 | DRD2 (0.58) | DRD2DRD4DRD3LMNASIGMAR1 | |
| SCHEMBL904854 | 0.83 | DRD3 (0.50) | DRD2DRD4DRD3LMNASIGMAR1 | |
| SCHEMBL8986083 | 0.83 | DRD2 (1.00) | DRD2DRD4DRD3 | |
| SCHEMBL904925 | 0.81 | OPRM1 (0.52) | DRD2DRD4DRD3LMNASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |