Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | IAPP | P10997 | 4/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | BID | P55957 | 2/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8405500 | 0.86 | ALDH1A1 (0.48) | GABRA1GABRB2ALOX5PTGS2ALDH1A1 | |
| SCHEMBL9049552 | 0.85 | GABRA1 (0.50) | GABRA1GABRB2ALOX5PTGS2ALDH1A1 | |
| SCHEMBL28950523 | 0.80 | HMGB1 (0.42) | GABRA1GABRB2ALOX5PTGS2ALDH1A1 | |
| SCHEMBL4100011 | 0.79 | TAAR1 (0.56) | MPOSLC6A4 | |
| SCHEMBL8894033 | 0.78 | GABRA1 (0.48) | GABRA1GABRB2ALOX5PTGS2IAPP | |
| SCHEMBL5589185 | 0.77 | ALOX5 (0.45) | ALOX5PTGS2IAPPHMGB1 | |
| SCHEMBL9153692 | 0.76 | ALOX5 (0.47) | GABRA1GABRB2ALOX5PTGS2IAPP | |
| SCHEMBL201764 | 0.76 | ALOX5 (0.61) | GABRA1GABRB2ALOX5PTGS2IAPP | |
| SCHEMBL11077986 | 0.74 | HSP90AA1 (0.53) | GABRA1GABRB2ALOX5PTGS2ALDH1A1 | |
| SCHEMBL2355153 | 0.74 | ALOX5 (0.70) | GABRA1GABRB2ALOX5PTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037535-A1 | METHOD OF PREPARING POLY(PHENYLENE OXIDES) IN CARBON DIOXIDE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-11-28 | — | — | WO | claimed |
| WO-1996037535-A1 | METHOD OF PREPARING POLY(PHENYLENE OXIDES) IN CARBON DIOXIDE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-11-28 | — | — | WO | disclosed |
| EP-0255230-B1 | PROCESS FOR PRODUCING POLYPHENYLENE ETHERS | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1992-10-14 | — | — | EP | disclosed |
| US-4895929-A | Process for producing polyphenylene ether, dispersing polyether in aqueous medium and heating dispersion | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1990-01-23 | — | — | US | disclosed |
| EP-0255230-A1 | Process for producing polyphenylene ethers | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1988-02-03 | — | — | EP | disclosed |
| EP-0059958-B1 | PROCESS FOR PRODUCING POLYPHENYLENE OXIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-06-04 | — | — | EP | disclosed |
| US-4588806-A | Polyphenylene ether resins having bimodal molecular weight distributions and method of their formation | GENERAL ELECTRIC COMPANY (US) | 1986-05-13 | — | — | US | disclosed |
| US-4385168-A | FROM OXIDATIVE POLYMERIZATION OF PHENOLIC MONOMER IN PRESENCE OF MANGANIUM SALT AND HYDROXYAZO AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-05-24 | — | — | US | disclosed |
| EP-0059958-A1 | Process for producing polyphenylene oxide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-09-15 | — | — | EP | disclosed |
| US-4098846-A | IMPACT STRENGTH | GENERAL ELECTRIC COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4054553-A | MANGANESE COMPLEX CATALYST | GENERAL ELECTRIC COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-3972851-A | Preparation of polyphenylene oxide using a manganese(II) ortho-hydroxyarene-oxime chelate reaction promoter | GENERAL ELECTRIC COMPANY (US) | 1976-08-03 | — | — | US | disclosed |
| US-3965069-A | Polyphenylene oxide is prepared using a mixture of manganese chelates as a catalyst | GENERAL ELECTRIC COMPANY (US) | 1976-06-22 | — | — | US | disclosed |
| US-3956242-A | Preparation of polyphenylene oxide using a manganese (II) ω-hydroxyoxime chelate reaction promoter | GENERAL ELECTRIC COMPANY (US) | 1976-05-11 | — | — | US | disclosed |