Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 6/20 | 0.32 |
| ▸ | DRD1 | P21728 | 3/20 | 0.32 |
| ▸ | DRD3 | P35462 | 3/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427490 | 0.79 | MEN1 (0.39) | PTGIRDRD2DRD1DRD3DRD4 | |
| SCHEMBL9046598 | 0.73 | POLB (0.41) | GHSRPTGIR | |
| SCHEMBL9045869 | 0.72 | LMNA (0.51) | LMNA | |
| SCHEMBL9049907 | 0.71 | MTNR1A (0.33) | GHSRDRD2DRD1DRD3CYP1A2 | |
| SCHEMBL9048633 | 0.69 | PTGIR (0.38) | GHSRPTGIRLMNA | |
| SCHEMBL9049796 | 0.67 | PTGIR (0.43) | PTGIR | |
| SCHEMBL9427232 | 0.66 | PTGIR (0.36) | PTGIRDRD2DRD3 | |
| SCHEMBL9049412 | 0.66 | ALDH1A1 (0.39) | PTGIRCA1CA2ACHE | |
| SCHEMBL9048134 | 0.65 | PTGIR (0.45) | PTGIR | |
| SCHEMBL9048118 | 0.65 | PTGIR (0.36) | PTGIRDRD2DRD3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |