Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 6/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | DRD1 | P21728 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050149 | 0.79 | GHSR (0.33) | LMNADRD2DRD3CA1CA2 | |
| SCHEMBL9427171 | 0.77 | PTGIR (0.39) | MEN1KMT2AS1PR5KDM4EGAA | |
| SCHEMBL9049907 | 0.71 | MTNR1A (0.33) | DRD2DRD3CA1CA2ACHE | |
| SCHEMBL9046598 | 0.70 | POLB (0.41) | KMT2APTGIR | |
| SCHEMBL9047644 | 0.69 | PTGIR (0.36) | KMT2ALMNADRD2DRD3TSHR | |
| SCHEMBL9045869 | 0.69 | LMNA (0.51) | MEN1KMT2AGAALMNAALDH1A1 | |
| SCHEMBL9050455 | 0.69 | DRD2 (0.39) | LMNADRD2DRD3TSHRDRD1 | |
| SCHEMBL9046065 | 0.68 | DRD2 (0.38) | LMNADRD2DRD3TSHRDRD1 | |
| SCHEMBL9050858 | 0.68 | ALDH1A1 (0.41) | ALDH1A1HTT | |
| SCHEMBL9048669 | 0.67 | MEN1 (0.42) | MEN1KMT2AKDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |