SCHEMBL9050658

SCHEMBL9050658

CCOC(=O)c1nc(C)[nH]c1-c1cccc(Cl)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.56
PTGES O14684 1/20 0.54
TRPM8 Q7Z2W7 1/20 0.53
GABRA2 P47869 2/20 0.51
GABRB2 P47870 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.47
JAK2 O60674 1/20 0.47
JAK3 P52333 1/20 0.47
ALDH1A1 P00352 3/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C19 P33261 2/20 0.47
HPGD P15428 1/20 0.47
XBP1 P17861 1/20 0.47
PIN1 Q13526 1/20 0.47
CYP2C9 P11712 1/20 0.47
TARBP2 Q15633 1/20 0.46
ALOX12 P18054 1/20 0.46
ELANE P08246 1/20 0.46
ALOX15 P16050 1/20 0.45
CSF1R P07333 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9893863 0.87 PIN1 (0.56) ALOX5PTGESTRPM8GABRA2GABRB2
SCHEMBL6494078 0.84 TARBP2 (0.56) GABRA2GABRB2ALDH1A1HPGDTARBP2
SCHEMBL10355344 0.80 ALDH1A1 (0.57) ALOX5PTGESTRPM8GABRA2GABRB2
SCHEMBL13398492 0.78 ALDH1A1 (0.59) ALOX5TRPM8GABRA2GABRB2L3MBTL1
SCHEMBL18004078 0.76 TARBP2 (0.62) ALOX5PTGESTRPM8GABRA2GABRB2
SCHEMBL4786522 0.75 ALOX5 (0.55) ALOX5PTGESTRPM8GABRA2GABRB2
SCHEMBL30740993 0.74 GCGR (0.63) ALOX5PTGESTRPM8GABRA2GABRB2
SCHEMBL6473195 0.74 TARBP2 (0.51) ALOX5PTGESGABRA2GABRB2ALDH1A1
SCHEMBL7991934 0.73 MAPT (0.52) GABRA2GABRB2L3MBTL1ALDH1A1HPGD
SCHEMBL9587212 0.72 ALOX5 (0.52) ALOX5TRPM8GABRA2GABRB2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0712847-A1 IMIDAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND PEST CONTROL DRUG NIPPON SODA CO., LTD. (JP) 1996-05-22 EP disclosed