Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 3/20 | 0.34 |
| ▸ | MMP3 | P08254 | 3/20 | 0.34 |
| ▸ | MASP2 | O00187 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033903 | 0.90 | MEN1 (0.34) | MEN1KMT2AANPEPDRD2DRD3 | |
| SCHEMBL9033444 | 0.82 | MAOA (0.41) | MEN1KMT2AANPEPMAOA | |
| SCHEMBL9033517 | 0.82 | POLB (0.40) | MEN1KMT2AANPEPPOLB | |
| SCHEMBL9033793 | 0.82 | — | — | |
| SCHEMBL9033478 | 0.80 | ANPEP (0.44) | MEN1KMT2AANPEPMASP2 | |
| SCHEMBL9050939 | 0.78 | GHSR (0.39) | MEN1KMT2AANPEPGHSR | |
| SCHEMBL9033512 | 0.76 | POLB (0.46) | MEN1KMT2AANPEPPOLB | |
| SCHEMBL9033473 | 0.76 | ANPEP (0.47) | MEN1KMT2AANPEPMMEMASP2 | |
| SCHEMBL9033807 | 0.73 | DPP4 (0.35) | MMEACECPA1ACE2 | |
| SCHEMBL9032688 | 0.72 | L3MBTL1 (0.33) | MEN1KMT2AMMEACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696593-A2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |