Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055896 | 0.87 | OPRM1 (0.44) | HDAC1HDAC8SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9055176 | 0.87 | DRD2 (0.43) | HDAC1HDAC8SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9052627 | 0.86 | DRD2 (0.57) | HDAC1HDAC8SMN1; SMN2DRD2HPGD | |
| SCHEMBL9051793 | 0.86 | DRD2 (0.47) | HDAC1HDAC8SMN1; SMN2MAPTMEN1 | |
| SCHEMBL9055744 | 0.84 | HPGD (0.49) | HDAC1HDAC8SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9053002 | 0.84 | OPRM1 (0.47) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL9052131 | 0.83 | DRD2 (0.42) | HDAC1HDAC8SMN1; SMN2MAPTMEN1 | |
| SCHEMBL8986025 | 0.83 | DRD2 (0.56) | HDAC1HDAC8SMN1; SMN2DRD2HPGD | |
| SCHEMBL9052477 | 0.82 | HTR1A (0.45) | HDAC1HDAC8SMN1; SMN2MAPTMEN1 | |
| SCHEMBL9053113 | 0.81 | DRD2 (0.56) | SMN1; SMN2MAPTALDH1A1HTTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002250-A1 | HALOPERIDOL ANALOGS AND THE USE THEREOF | ACEA PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |