Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055176 | 0.85 | DRD2 (0.43) | HPGDSMN1; SMN2L3MBTL1DRD2HDAC1 | |
| SCHEMBL9055896 | 0.85 | OPRM1 (0.44) | HPGDSMN1; SMN2L3MBTL1DRD2HDAC1 | |
| SCHEMBL9051252 | 0.84 | HDAC1 (0.43) | HPGDSMN1; SMN2L3MBTL1DRD2ALDH1A1 | |
| SCHEMBL9052627 | 0.84 | DRD2 (0.57) | HPGDSMN1; SMN2L3MBTL1DRD2HDAC1 | |
| SCHEMBL9051793 | 0.84 | DRD2 (0.47) | HPGDSMN1; SMN2L3MBTL1DRD2ALDH1A1 | |
| SCHEMBL8986025 | 0.83 | DRD2 (0.56) | HPGDSMN1; SMN2L3MBTL1DRD2HDAC1 | |
| SCHEMBL9053002 | 0.82 | OPRM1 (0.47) | DRD2ALDH1A1HTR1AMAPT | |
| SCHEMBL9053069 | 0.81 | SMN1; SMN2 (0.51) | HPGDSMN1; SMN2L3MBTL1DRD2SLC6A2 | |
| SCHEMBL9052131 | 0.81 | DRD2 (0.42) | HPGDSMN1; SMN2L3MBTL1DRD2MAPK1 | |
| SCHEMBL9052477 | 0.81 | HTR1A (0.45) | HPGDSMN1; SMN2L3MBTL1DRD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002250-A1 | HALOPERIDOL ANALOGS AND THE USE THEREOF | ACEA PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |