Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.47 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.47 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.47 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055176 | 0.85 | DRD2 (0.43) | OPRM1OPRD1OPRK1OPRL1HTR1A | |
| SCHEMBL9055896 | 0.85 | OPRM1 (0.44) | OPRM1OPRD1OPRK1OPRL1HTR1A | |
| SCHEMBL9052627 | 0.84 | DRD2 (0.57) | OPRM1OPRD1OPRK1OPRL1HTR1A | |
| SCHEMBL9051252 | 0.84 | HDAC1 (0.43) | HTR1AKMT2AMEN1DRD2ALDH1A1 | |
| SCHEMBL9051793 | 0.84 | DRD2 (0.47) | OPRM1OPRD1OPRK1OPRL1HTR1A | |
| SCHEMBL9055744 | 0.82 | HPGD (0.49) | HTR1ADRD2ALDH1A1MAPT | |
| SCHEMBL9052131 | 0.81 | DRD2 (0.42) | SIGMAR1HTR1AKMT2AMEN1DRD2 | |
| SCHEMBL8986025 | 0.81 | DRD2 (0.56) | OPRM1OPRD1OPRK1OPRL1HTR1A | |
| SCHEMBL9052477 | 0.81 | HTR1A (0.45) | HTR1AKMT2AMEN1POLBDRD2 | |
| SCHEMBL9052266 | 0.80 | MEN1 (0.58) | SIGMAR1HTR1AKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002250-A1 | HALOPERIDOL ANALOGS AND THE USE THEREOF | ACEA PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |