Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052278 | 0.83 | MMP8 (0.50) | KMT2AMMP8MMEMEN1 | |
| SCHEMBL27660866 | 0.81 | EPHX1 (0.46) | ALDH1A1EPHX1ALPIPKMPTGS1 | |
| SCHEMBL28026869 | 0.81 | EPHX1 (0.46) | ALDH1A1EPHX1ALPIPKMPTGS1 | |
| SCHEMBL3135798 | 0.79 | ACE (0.42) | KMT2AMMP8MME | |
| SCHEMBL7491376 | 0.78 | LMNA (0.41) | BCAT2METAP2METAP1PKMMMP8 | |
| SCHEMBL27640137 | 0.77 | PKM (0.44) | PKMKMT2AGAAMMP8POLB | |
| SCHEMBL8666884 | 0.77 | CYP1A2 (0.47) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL6341817 | 0.76 | METAP2 (0.36) | METAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL27916346 | 0.76 | CETP (0.40) | ALDH1A1KMT2AGAAPOLBMEN1 | |
| SCHEMBL27640144 | 0.75 | SMN1; SMN2 (0.50) | ALDH1A1EPHX1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996039385-A1 | SUBSTITUTED N-(INDOLE-2-CARBONYL-) AMIDES AND DERIVATIVES AS GLYCOGEN PHOSPHORYLASE INHIBITORS | PFIZER INC. (US) | 1996-12-12 | — | — | WO | disclosed |