Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 5/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27640137 | 0.83 | PKM (0.44) | MMP8MMETSHRMEN1KMT2A | |
| SCHEMBL9051266 | 0.83 | BCAT2 (0.39) | MMP8MMEMEN1KMT2A | |
| SCHEMBL8666884 | 0.82 | CYP1A2 (0.47) | MME | |
| SCHEMBL27640144 | 0.80 | SMN1; SMN2 (0.50) | TSHRKMT2A | |
| SCHEMBL27660866 | 0.79 | EPHX1 (0.46) | — | |
| SCHEMBL28026869 | 0.79 | EPHX1 (0.46) | — | |
| SCHEMBL27640133 | 0.79 | BACE1 (0.41) | MMP8MMETSHRHDAC6HDAC3 | |
| SCHEMBL3135798 | 0.78 | ACE (0.42) | MMP8MMETSHRKMT2A | |
| SCHEMBL4070246 | 0.78 | MMP8 (0.51) | MMP8MMEHDAC8HDAC6HDAC3 | |
| SCHEMBL7491376 | 0.77 | LMNA (0.41) | MMP8MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996039385-A1 | SUBSTITUTED N-(INDOLE-2-CARBONYL-) AMIDES AND DERIVATIVES AS GLYCOGEN PHOSPHORYLASE INHIBITORS | PFIZER INC. (US) | 1996-12-12 | — | — | WO | disclosed |