Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17555020 | 0.72 | INMT (0.31) | — | |
| SCHEMBL1023795 | 0.63 | ALDH1A1 (0.59) | ALDH1A1 | |
| SCHEMBL27512628 | 0.61 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL5711878 | 0.61 | CHRNB2 (0.38) | — | |
| SCHEMBL29285276 | 0.60 | DRD3 (0.36) | ALDH1A1 | |
| SCHEMBL9737172 | 0.60 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL28132486 | 0.60 | ALDH1A1 (0.51) | ALDH1A1 | |
| SCHEMBL9567812 | 0.60 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL218212 | 0.60 | SLC6A2 (0.46) | ALDH1A1 | |
| SCHEMBL4189196 | 0.60 | SLC18A3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3250208-A1 | 7-BENZYL-4-(2-METHYLBENZYL)-2,4,6,7,8,9-HEXAHYDROIMIDAZO [1,2-A]PYRIDO[3,4-E]PYRIMIDIN-5(1H)-ONE, ANALOGS AND SALTS THEREOF AND THEIR USE IN THERAPY | Oncoceutics, Inc. (US) | 2017-12-06 | — | — | EP | disclosed |
| WO-2016123571-A1 | 7-BENZYL-4-(2-METHYLBENZYL)-2,4,6,7,8,9-HEXAHYDROIMIDAZO [1,2-A]PYRIDO[3,4-E]PYRIMIDIN-5(1H)-ONE, ANALOGS AND SALTS THEREOF AND THEIR USE IN THERAPY | ONCOCEUTICS INC. (US) | 2016-08-04 | — | — | WO | disclosed |
| WO-1996040753-A1 | PIPECOLIC ACID DERIVATIVES OF PROLINE THREONINE AMIDES USEFUL FOR THE TREATMENT OF RHEUMATOID ARTHRITIS | G.D. SEARLE & CO. (US) | 1996-12-19 | — | — | WO | disclosed |