Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SOD1 | P00441 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052266 | 0.87 | MEN1 (0.58) | ALDH1A1KMT2AMEN1SMN1; SMN2HTR1A | |
| SCHEMBL9052260 | 0.86 | OPRM1 (0.46) | ALDH1A1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9055948 | 0.85 | DRD2 (0.51) | ALDH1A1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9053424 | 0.85 | DRD2 (0.44) | ALDH1A1KMT2ASMN1; SMN2DRD2LMNA | |
| SCHEMBL9053432 | 0.85 | DRD2 (0.44) | ALDH1A1OPRM1OPRK1OPRL1SMN1; SMN2 | |
| SCHEMBL9051376 | 0.85 | DRD2 (0.59) | DRD4DRD2HTR1A | |
| SCHEMBL8986025 | 0.84 | DRD2 (0.56) | OPRM1OPRD1OPRK1OPRL1SMN1; SMN2 | |
| SCHEMBL9053069 | 0.84 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2DRD2 | |
| SCHEMBL9053341 | 0.82 | ABCB11 (0.62) | ALDH1A1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9053118 | 0.81 | HTR1A (0.46) | ALDH1A1KMT2AMEN1SMN1; SMN2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002250-A1 | HALOPERIDOL ANALOGS AND THE USE THEREOF | ACEA PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |