Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 7/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8986025 | 0.90 | DRD2 (0.56) | SMN1; SMN2HPGDL3MBTL1DRD2HDAC1 | |
| SCHEMBL9052260 | 0.87 | OPRM1 (0.46) | SMN1; SMN2HPGDDRD2MAPK1CYP2D6 | |
| SCHEMBL9051376 | 0.86 | DRD2 (0.59) | DRD2MAPK1CYP2D6CYP3A4TSHR | |
| SCHEMBL9053432 | 0.86 | DRD2 (0.44) | SMN1; SMN2DRD2MAPK1CYP1A2CYP2D6 | |
| SCHEMBL9055948 | 0.86 | DRD2 (0.51) | SMN1; SMN2HPGDDRD2USP2MAPK1 | |
| SCHEMBL9053424 | 0.86 | DRD2 (0.44) | SMN1; SMN2HPGDDRD2MAPK1CYP2D6 | |
| SCHEMBL9051909 | 0.84 | ALDH1A1 (0.53) | SMN1; SMN2DRD2ALDH1A1 | |
| SCHEMBL9053341 | 0.83 | ABCB11 (0.62) | SMN1; SMN2DRD2USP2MAPK1CYP2D6 | |
| SCHEMBL9053118 | 0.82 | HTR1A (0.46) | SMN1; SMN2HPGDL3MBTL1DRD2MAPK1 | |
| SCHEMBL9055744 | 0.81 | HPGD (0.49) | SMN1; SMN2HPGDL3MBTL1DRD2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002250-A1 | HALOPERIDOL ANALOGS AND THE USE THEREOF | ACEA PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |