Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 8/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 8/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056774 | 0.68 | CHRNB2 (0.33) | POLB | |
| SCHEMBL9052242 | 0.64 | L3MBTL1 (0.35) | MEN1KMT2APOLBMAPTL3MBTL1 | |
| SCHEMBL30845989 | 0.63 | MEN1 (0.40) | GNAI3GNAI1GNAO1MEN1KMT2A | |
| SCHEMBL28369766 | 0.60 | GNAI3 (0.43) | GNAI3GNAI1GNAO1MEN1KMT2A | |
| SCHEMBL852318 | 0.60 | GNAI3 (0.46) | GNAI3GNAI1GNAO1MEN1KMT2A | |
| SCHEMBL9224930 | 0.59 | GNAI3 (0.84) | GNAI3GNAI1GNAO1MEN1KMT2A | |
| SCHEMBL27859371 | 0.58 | GNAI3 (0.50) | GNAI3GNAI1GNAO1MEN1KMT2A | |
| SCHEMBL22874721 | 0.57 | GNAI3 (0.57) | GNAI3GNAI1GNAO1MEN1KMT2A | |
| SCHEMBL9280678 | 0.57 | GNAI3 (0.57) | GNAI3GNAI1GNAO1MEN1KMT2A | |
| SCHEMBL673399 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031217-A9 | INHIBITING RETROVIRAL REPLICATION | — | 1996-11-28 | — | — | WO | claimed |
| WO-1996002241-A9 | USE OF NITROGEN OXIDE SPECIES AND ADDUCTS TO INHIBIT SKELETAL MUSCLE CONTRACTION | — | 1996-02-29 | — | — | WO | claimed |
| WO-1996038136-A1 | LOCALIZED USE OF NITRIC OXIDE-ADDUCTS TO PREVENT INTERNAL TISSUE DAMAGE | NITROMED INC (US) | 1996-12-05 | — | — | WO | disclosed |
| WO-1996035416-A1 | LOCALIZED USE OF NITRIC OXIDEADDUCTS TO PREVENT INTERNAL TISSUE DAMAGE | NITROMED, INC. (US) | 1996-11-14 | — | — | WO | disclosed |