Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL89138 | 0.82 | — | — | |
| SCHEMBL175063 | 0.79 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL11286675 | 0.75 | ALDH1A1 (0.42) | ALDH1A1BLM | |
| SCHEMBL15324519 | 0.74 | CRHR1 (0.41) | ALDH1A1TSPO | |
| SCHEMBL7047586 | 0.72 | CNR1 (0.41) | ALDH1A1 | |
| SCHEMBL11466649 | 0.71 | ALDH1A1 (0.48) | ALDH1A1 | |
| SCHEMBL7069055 | 0.70 | ALDH1A1 (0.39) | ALDH1A1BLMTSPO | |
| SCHEMBL460383 | 0.70 | TSHR (0.38) | ALDH1A1 | |
| SCHEMBL11126424 | 0.67 | ALDH1A1 (0.48) | ALDH1A1BLMTSPO | |
| SCHEMBL43166 | 0.67 | MAPT (0.38) | ALDH1A1TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129444-B2 | Self-adhesive dental materials | 3M ESPE AG (DE) | 2012-03-06 | — | — | US | claimed |
| WO-2024121658-A1 | SURFACE-TREATED FILLER, DENTAL COMPOSITION CONTAINING SUCH A FILLER, PROCESS OF PRODUCTION AND USE THEREOF | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-06-13 | — | — | WO | disclosed |
| US-11998417-B2 | Process for producing a surface-modified dental article | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-06-04 | — | — | US | disclosed |
| US-11992539-B2 | Curable dental compositions and uses thereof | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-05-28 | — | — | US | disclosed |
| EP-4362881-A1 | DENTAL CEMENT COMPOSITION, KIT OF PARTS AND USE THEREOF | 3M Innovative Properties Company (US) | 2024-05-08 | — | — | EP | disclosed |
| WO-2024057144-A1 | DENTAL PRODUCT WITH REDUCED EXTRUSION FORCES | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-03-21 | — | — | WO | disclosed |
| US-20230404861-A1 | CURABLE DENTAL COMPOSITIONS AND USES THEREOF | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2023-12-21 | — | — | US | disclosed |
| EP-4251117-A1 | CURABLE DENTAL COMPOSITIONS AND USES THEREOF | 3M Innovative Properties Company (US) | 2023-10-04 | — | — | EP | disclosed |
| US-20230225829-A1 | PROCESS FOR PRODUCING A SURFACE-MODIFIED DENTAL ARTICLE | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2023-07-20 | — | — | US | disclosed |
| EP-4175584-A1 | PROCESS FOR PRODUCING A SURFACE-MODIFIED DENTAL ARTICLE | 3M Innovative Properties Company (US) | 2023-05-10 | — | — | EP | disclosed |
| US-5968998-A | ADDITIONALLY CONTAINING SPECIFIED UNSATURATED ARYL COMPOUND TO LENGTHEN SETTING TIME | ESPE STIFTUNG & CO. PRODUKTIONS-UND VERTRIEBS KG (DE) | 1999-10-19 | — | — | US | disclosed |
| WO-1999024477-A1 | POLYMERIZABLE COMPOSITION AND THE APPLICATION THEREOF AS A COUPLING AGENT | ESPE DENTAL AG (DE) | 1999-05-20 | — | — | WO | disclosed |
| US-5824720-A | DI OR MULTI(METH)ACRYLATES, INITIATORS, ACTIVATORS, FILLERS AND FLUORIDE COMPLEXES FOR DENTAL FILLING | THERA PATENT GMBH & CO. KG GESELLSCHAFT FUR INDUSTRIELLE SCHUTZRECHTE (DE) | 1998-10-20 | — | — | US | disclosed |
| US-5583164-A | FREE RADICAL POLYMERIZATION; DELAY CURING | ESPE STIFTUNG & CO. PRODUKTIONS-UND VERTRIEBS KG (DE) | 1996-12-10 | — | — | US | disclosed |
| EP-0717977-A2 | Fluoride releasing dental composite material | THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte (DE) | 1996-06-26 | — | — | EP | disclosed |
| EP-0374824-B1 | DENTAL COMPOSITIONS CONTAINING BIFUNCTIONAL ACRYLIC OR METHACRYLIC ACID ESTERS | THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte (DE) | 1993-09-22 | — | — | EP | disclosed |
| EP-0374824-A2 | Dental compositions containing bifunctional acrylic or methacrylic acid esters | THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte (DE) | 1990-06-27 | — | — | EP | disclosed |
| US-4323348-A | Dental compositions | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-06 | — | — | US | disclosed |
| EP-0023685-A2 | Dental masses | BAYER AG (DE) | 1981-02-11 | — | — | EP | disclosed |
| US-4095018-A | POLYACRYLIC ACIDS AND ESTERS | ESPE FABRIK PHARMAZEUTISCHER PRAPARATE GMBH (DT) | 1978-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230404861-A1 | CURABLE DENTAL COMPOSITIONS AND USES THEREOF | H1-0, COL1A1, HAX1 | ALDH1A1 576/4885BLM 828/4885TSPO 4166/4885 |
| US-11992539-B2 | Curable dental compositions and uses thereof | H1-0, COL1A1, HAX1 | ALDH1A1 576/4885BLM 828/4885TSPO 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.