SCHEMBL43166

SCHEMBL43166

Cc1cc(C)cc(N(CCO)CCO)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.38
KMT2A Q03164 4/20 0.38
LMNA P02545 3/20 0.38
MEN1 O00255 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
POLB P06746 2/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
GAA P10253 1/20 0.38
PKM P14618 1/20 0.38
HTT P42858 1/20 0.38
MCL1 Q07820 1/20 0.38
MAPK1 P28482 1/20 0.38
MMP14 P50281 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 5/20 0.36
TSPO P30536 2/20 0.34
TP53 P04637 1/20 0.34
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14028574 0.92 CRHR1 (0.43) MAPTKMT2ALMNAMEN1SMN1; SMN2
SCHEMBL12852072 0.89 KMT2A (0.42) MAPTKMT2ALMNAMEN1SMN1; SMN2
SCHEMBL11122141 0.86 HPGD (0.37) MAPTKMT2ALMNAMEN1SMN1; SMN2
SCHEMBL18278561 0.86 MAPT (0.34) MAPTKMT2ALMNAMEN1SMN1; SMN2
SCHEMBL14003144 0.84 TSPO (0.33) MAPTKMT2ALMNAMEN1SMN1; SMN2
SCHEMBL7641851 0.82 TSPO (0.38) MAPTKMT2ALMNAMEN1SMN1; SMN2
SCHEMBL7069055 0.80 ALDH1A1 (0.39) POLBGAAL3MBTL1ALDH1A1TSPO
SCHEMBL6226015 0.79 MAPT (0.44) MAPTKMT2ALMNAMEN1SMN1; SMN2
SCHEMBL10712858 0.79 ALDH1A1 (0.39) MAPTKMT2AMEN1POLBHTT
SCHEMBL632177 0.79 MAPT (0.44) MAPTKMT2ALMNAMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 684 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119552299-A Method for realizing anti-caking of acrylic resin powder 博立尔化工(扬州)有限公司 2025-03-04 CN claimed
CN-119552300-A Method for realizing anti-caking of acrylic resin powder by chemical doping method 博立尔化工(扬州)有限公司 2025-03-04 CN claimed
WO-2008122596-A2 CURABLE THERAPEUTIC IMPLANT COMPOSITION CINVENTION AG (DE) 2008-10-16 WO claimed
US-20080248086-A1 CURABLE THERAPEUTIC IMPLANT COMPOSITION CINVENTION AG (DE) 2008-10-09 US claimed
US-5204398-A High compressive strength ESSENTIAL DENTAL SYSTEMS, INC. (US) 1993-04-20 US claimed
EP-0476110-A4 COMPOSITE DENTAL CEMENT COMPOSITION CONTAINING TITANIUM 1992-11-25 EP claimed
EP-0476110-A1 COMPOSITE DENTAL CEMENT COMPOSITION CONTAINING TITANIUM ESSENTIAL DENTAL SYSTEMS, INC. (US) 1992-03-25 EP claimed
WO-1991015183-A1 COMPOSITE DENTAL CEMENT COMPOSITION CONTAINING TITANIUM ESSENTIAL DENTAL SYSTEMS, INC. (US) 1991-10-17 WO claimed
US-5034433-A Forming polyepoxides and acrylic matrices for dentistry ESSENTIAL DENTAL SYSTEMS, INC. (US) 1991-07-23 US claimed
US-20260144714-A1 KIT FOR PREPARING CURABLE COMPOSITION FOR DENTAL MATERIAL, CURABLE COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2026-05-28 US disclosed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
US-20260124121-A1 POLYMERIZABLE DENTAL COMPOSITION TROETSCHLER TOBIAS (DE) 2026-05-07 US disclosed
EP-3861977-B1 (METH)ACRYLATE, MONOMER COMPOSITION, MOLDED BODY, COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL MITSUI CHEMICALS INC (JP) 2026-05-06 EP disclosed
EP-4736833-A1 POLYMERIZABLE DENTAL COMPOSITION DENTSPLY SIRONA Inc. (US) 2026-05-06 EP disclosed
EP-0017937-A2 Bonding compositions to the hard tissue of human body KANEBO, LTD. (JP) 1980-10-29 EP disclosed
EP-0017151-A2 Cold curing materials for dental purposes with polymerisation-active sulfones BAYER AG (DE) 1980-10-15 EP disclosed
US-4144027-A SHRINKPROOFING KERATIN-CONTAINING FABRICS BY REACTION WITH A POLYETHER POLYOL AND A DIISOCYANATE MILLIKEN RESEARCH CORPORATION (US) 1979-03-13 US disclosed
US-4142038-A N,N-DIALKANOLBENZAMIDES, DIISOCYANATES, DICARBOXYLIC ACIDS BAYER AKTIENGESELLSCHAFT (DE) 1979-02-27 US disclosed
US-4134930-A SLURRYING A METHACRYLATE RESIN WITH A BIS/(METHACRYLOXYPOLYETHOXY) PHENYL/PROPANE G-C DENTAL INDUSTRIAL CORP. (JP) 1979-01-16 US disclosed
US-4095018-A POLYACRYLIC ACIDS AND ESTERS ESPE FABRIK PHARMAZEUTISCHER PRAPARATE GMBH (DT) 1978-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144714-A1 KIT FOR PREPARING CURABLE COMPOSITION FOR DENTAL MATERIAL, CURABLE COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL CAD, KIT, ILK MAPT 3535/4885KMT2A 270/4885LMNA 1719/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL MAPT 4304/4885KMT2A 2306/4885LMNA 2975/4885
US-20260124121-A1 POLYMERIZABLE DENTAL COMPOSITION F12, RAD51, PFN1 MAPT 999/4885KMT2A 3311/4885LMNA 1130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.