SCHEMBL905273

SCHEMBL905273

[CH2]CC[Si](C)(OCCCC)OCCCC

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
CYP2D6 P10635 3/20 0.31
CYP3A4 P08684 2/20 0.31
CYP1A2 P05177 2/20 0.30
CYP19A1 P11511 2/20 0.30
CYP2C9 P11712 2/20 0.30
CYP2C19 P33261 2/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4079096 0.86
SCHEMBL703594 0.85 ADRB2 (0.39) ADRB2ADRB1ADRB3CYP2D6CYP3A4
SCHEMBL28805966 0.83 ADRB2 (0.38) ADRB2ADRB1ADRB3CYP3A4TSHR
SCHEMBL705364 0.83 ADRB2 (0.38) ADRB2ADRB1ADRB3CYP3A4TSHR
SCHEMBL1595849 0.83 ADRB2 (0.38) ADRB2ADRB1ADRB3CYP3A4TSHR
SCHEMBL706695 0.83 ADRB2 (0.38) ADRB2ADRB1ADRB3CYP3A4TSHR
SCHEMBL4090916 0.83 ADRB2 (0.38) ADRB2ADRB1ADRB3CYP3A4TSHR
SCHEMBL28062726 0.82 ADRB2 (0.33) ADRB2ADRB1ADRB3CYP3A4TSHR
SCHEMBL2125841 0.79 ADRB2 (0.35) ADRB2ADRB1ADRB3CYP3A4TSHR
SCHEMBL11332073 0.79 THRB (0.38) ADRB2ADRB1ADRB3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1915399-B1 RECOVERABLE POLYMER-BOUND HOMOGENEOUS CATALYSTS FOR CATALYTIC CHAIN TRANSFER PROCESSES COATINGS FOREIGN IP CO LLC (US) 2013-11-20 EP claimed
US-8030422-B2 Recoverable polymer-bound homogeneous catalysts for catalytic chain transfer process E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-10-04 US claimed
EP-2272885-A2 Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom Lubrizol Advanced Materials, Inc. (US) 2011-01-12 EP claimed
EP-1915399-A1 RECOVERABLE POLYMER-BOUND HOMOGENEOUS CATALYSTS FOR CATALYTIC CHAIN TRANSFER PROCESSES E.I.Du pont de nemours and company (US) 2008-04-30 EP claimed
WO-2007024634-A1 RECOVERABLE POLYMER-BOUND HOMOGENEOUS CATALYSTS FOR CATALYTIC CHAIN TRANSFER PROCESSES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-03-01 WO claimed
EP-0791016-A1 POLYMER SYNTHESIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-08-27 EP claimed
WO-1996015157-A1 POLYMER SYNTHESIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-05-23 WO claimed
EP-2970538-B1 POLYMERIZATION PROCESS PROTECTION MEANS DUPONT ELECTRONICS INC (US) 2021-10-20 EP disclosed
CN-107428955-B Proton binding polymers for oral administration 特里赛达公司 2021-09-21 CN disclosed
US-9925214-B2 Proton-binding polymers for oral administration TRICIDA, INC. (US) 2018-03-27 US disclosed
WO-2016123675-A1 TARGETING CONSTRUCTS FOR DELIVERY OF PAYLOADS THE UNIVERSITY OF QUEENSLAND (AU) 2016-08-11 WO disclosed
CN-105555901-A Polishing composition FUJIMI INC 2016-05-04 CN disclosed
US-20160074430-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION RENIBUS THERAPEUTICS, INC. 2016-03-17 US disclosed
WO-2007070724-A2 PIGMENT DISPERSIONS CONTAINING AMINATED ACRYLIC MACROMONOMER DISPERSANT E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-06-21 WO disclosed
EP-1786552-A1 METHOD OF MAKING POLYMER MONOLITH COMPOSITE SUBSTRATE AND RESULTING SUBSTRATE AS WELL AS BEADS AND BEAD ARRAY Applera Corporation (US) 2007-05-23 EP disclosed
WO-2007024634-A1 RECOVERABLE POLYMER-BOUND HOMOGENEOUS CATALYSTS FOR CATALYTIC CHAIN TRANSFER PROCESSES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-03-01 WO disclosed
US-20060078983-A1 Polymer monolith substrate APPLERA CORPORATION (US) 2006-04-13 US disclosed
EP-1639019-A1 PRESSURIZED HIGH TEMPERATURE POLYMERIZATION PROCESS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-03-29 EP disclosed
WO-2006026378-A1 METHOD OF MAKING POLYMER MONOLITH COMPOSITE SUBSTRATE AND RESULTING SUBSTRATE AS WELL AS BEADS AND BEAD ARRAY APPLERA CORPORATION (US) 2006-03-09 WO disclosed
WO-2005003185-A1 PRESSURIZED HIGH TEMPERATURE POLYMERIZATION PROCESS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160074430-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION SLC9A1, HRH2, SLC9A2 ADRB2 4338/4885ADRB1 4371/4885ADRB3 3764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.