SCHEMBL9053535

SCHEMBL9053535

Cc1ccc(S(=O)(=O)Oc2ccc(C(=O)O)cc2N)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.51
GAA P10253 6/20 0.48
MAPT P10636 3/20 0.48
ALDH1A1 P00352 4/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
GFER P55789 2/20 0.48
NPC1 O15118 2/20 0.48
KDM4E B2RXH2 1/20 0.48
KMT2A Q03164 3/20 0.47
STAT3 P40763 1/20 0.46
EGFR P00533 2/20 0.45
ABL1 P00519 1/20 0.45
ABL2 P42684 1/20 0.45
G6PD P11413 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MEN1 O00255 2/20 0.44
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
PKM P14618 2/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9053528 0.85 CYP1A2 (0.50) CYP1A2GAAMAPTALDH1A1SMN1; SMN2
SCHEMBL15443118 0.84 CYP1A2 (0.56) CYP1A2GAAMAPTALDH1A1SMN1; SMN2
SCHEMBL18506128 0.83 RAB9A (0.55) CYP1A2GAAMAPTALDH1A1SMN1; SMN2
SCHEMBL9054847 0.82 HTT (0.54) CYP1A2GAAMAPTALDH1A1SMN1; SMN2
SCHEMBL13167860 0.80 TSHR (0.54) GAAMAPTALDH1A1KMT2AEGFR
SCHEMBL9053867 0.79 ALDH1A1 (0.48) CYP1A2GAAMAPTALDH1A1SMN1; SMN2
SCHEMBL14872758 0.78 ALDH1A1 (0.49) CYP1A2GAAMAPTALDH1A1SMN1; SMN2
SCHEMBL1665713 0.76 MEN1 (0.70) GAAMAPTALDH1A1SMN1; SMN2GFER
SCHEMBL30899144 0.76 MEN1 (0.64) GAAMAPTSMN1; SMN2GFERKDM4E
SCHEMBL7937565 0.76 PTGS2 (0.51) CYP1A2GAAMAPTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996008483-A1 GALLIC ACID DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS DRUGS ROUSSEL UCLAF (FR) 1996-03-21 WO disclosed